Knockdown of heat shock protein family D member 1 (HSPD1) promotes proliferation and migration of ovarian cancer cells via disrupting the stability of mitochondrial 3-oxoacyl-ACP synthase (OXSM)

• Main Authors: Yaoyun Duan (Author), Juan Yu (Author), Miaojuan Chen (Author), Qinsheng Lu (Author), Fen Ning (Author), Xiaowen Gan (Author), Hanbo Liu (Author), Yixin Ye (Author), Shenjiao Lu (Author), Gendie E. Lash (Author)
• Format: Book
• Published: BMC, 2023-04-01T00:00:00Z.
• Subjects: article
• Online Access: Connect to this object online.

Abstract Background Heat shock protein 60 (HSP60) is essential for the folding and assembly of newly imported proteins to the mitochondria. HSP60 is overexpressed in most types of cancer, but its association with ovarian cancer is still in dispute. SKOV3 and OVCAR3 were used as experimental models a...