Effects of the selective AMPA modulator NBI‐1065845 on the pharmacokinetics of midazolam or ethinyl estradiol-levonorgestrel in healthy adults

• Autors principals: Swan Lin (Autor), Adrian Ionescu (Autor), Jessica Maynard‐Scott (Autor), Mike Kennedy (Autor), David P. Walling (Autor), Maura Furey (Autor), Jaskaran B. Singh (Autor)
• Format: Llibre
• Publicat: Wiley, 2024-05-01T00:00:00Z.
• Matèries: article
• Accés en línia: Connect to this object online.

Abstract This parallel‐arm, phase I study investigated the potential cytochrome P450 (CYP)3A induction effect of NBI‐1065845 (TAK‐653), an investigational α‐amino‐3‐hydroxy‐5‐methyl‐4‐isoxazolepropionic acid receptor potentiator in phase II development for major depressive disorder. The midazolam tr...