Discovery of New Potent anti-MERS CoV Fusion Inhibitors

• المؤلفون الرئيسيون: Mahmoud Kandeel (مؤلف), Mizuki Yamamoto (مؤلف), Byoung Kwon Park (مؤلف), Abdulla Al-Taher (مؤلف), Aya Watanabe (مؤلف), Jin Gohda (مؤلف), Yasushi Kawaguchi (مؤلف), Kentaro Oh-hashi (مؤلف), Hyung-Joo Kwon (مؤلف), Jun-ichiro Inoue (مؤلف)
• التنسيق: كتاب
• منشور في: Frontiers Media S.A., 2021-06-01T00:00:00Z.
• الموضوعات: article
• الوصول للمادة أونلاين: Connect to this object online.

Middle East respiratory syndrome coronavirus (MERS-CoV), capable of zoonotic transmission, has been associated with emerging viral pneumonia in humans. In this study, a set of highly potent peptides were designed to prevent MERS-CoV fusion through competition with heptad repeat domain 2 (HR2) at its...