Discovery of New Potent anti-MERS CoV Fusion Inhibitors

• Κύριοι συγγραφείς: Mahmoud Kandeel (Συγγραφέας), Mizuki Yamamoto (Συγγραφέας), Byoung Kwon Park (Συγγραφέας), Abdulla Al-Taher (Συγγραφέας), Aya Watanabe (Συγγραφέας), Jin Gohda (Συγγραφέας), Yasushi Kawaguchi (Συγγραφέας), Kentaro Oh-hashi (Συγγραφέας), Hyung-Joo Kwon (Συγγραφέας), Jun-ichiro Inoue (Συγγραφέας)
• Μορφή: Βιβλίο
• Έκδοση: Frontiers Media S.A., 2021-06-01T00:00:00Z.
• Θέματα: article
• Διαθέσιμο Online: Connect to this object online.

Middle East respiratory syndrome coronavirus (MERS-CoV), capable of zoonotic transmission, has been associated with emerging viral pneumonia in humans. In this study, a set of highly potent peptides were designed to prevent MERS-CoV fusion through competition with heptad repeat domain 2 (HR2) at its...