Discovery of New Potent anti-MERS CoV Fusion Inhibitors

• Egile Nagusiak: Mahmoud Kandeel (Egilea), Mizuki Yamamoto (Egilea), Byoung Kwon Park (Egilea), Abdulla Al-Taher (Egilea), Aya Watanabe (Egilea), Jin Gohda (Egilea), Yasushi Kawaguchi (Egilea), Kentaro Oh-hashi (Egilea), Hyung-Joo Kwon (Egilea), Jun-ichiro Inoue (Egilea)
• Formatua: Liburua
• Argitaratua: Frontiers Media S.A., 2021-06-01T00:00:00Z.
• Gaiak: article
• Sarrera elektronikoa: Connect to this object online.

Middle East respiratory syndrome coronavirus (MERS-CoV), capable of zoonotic transmission, has been associated with emerging viral pneumonia in humans. In this study, a set of highly potent peptides were designed to prevent MERS-CoV fusion through competition with heptad repeat domain 2 (HR2) at its...