Discovery of New Potent anti-MERS CoV Fusion Inhibitors

• 主要な著者: Mahmoud Kandeel (著者), Mizuki Yamamoto (著者), Byoung Kwon Park (著者), Abdulla Al-Taher (著者), Aya Watanabe (著者), Jin Gohda (著者), Yasushi Kawaguchi (著者), Kentaro Oh-hashi (著者), Hyung-Joo Kwon (著者), Jun-ichiro Inoue (著者)
• フォーマット: 図書
• 出版事項: Frontiers Media S.A., 2021-06-01T00:00:00Z.
• 主題: article
• オンライン･アクセス: Connect to this object online.

Middle East respiratory syndrome coronavirus (MERS-CoV), capable of zoonotic transmission, has been associated with emerging viral pneumonia in humans. In this study, a set of highly potent peptides were designed to prevent MERS-CoV fusion through competition with heptad repeat domain 2 (HR2) at its...