Discovery of New Potent anti-MERS CoV Fusion Inhibitors

• Váldodahkkit: Mahmoud Kandeel (Dahkki), Mizuki Yamamoto (Dahkki), Byoung Kwon Park (Dahkki), Abdulla Al-Taher (Dahkki), Aya Watanabe (Dahkki), Jin Gohda (Dahkki), Yasushi Kawaguchi (Dahkki), Kentaro Oh-hashi (Dahkki), Hyung-Joo Kwon (Dahkki), Jun-ichiro Inoue (Dahkki)
• Materiálatiipa: Girji
• Almmustuhtton: Frontiers Media S.A., 2021-06-01T00:00:00Z.
• Fáttát: article
• Liŋkkat: Connect to this object online.

Middle East respiratory syndrome coronavirus (MERS-CoV), capable of zoonotic transmission, has been associated with emerging viral pneumonia in humans. In this study, a set of highly potent peptides were designed to prevent MERS-CoV fusion through competition with heptad repeat domain 2 (HR2) at its...