Curcumin Stereoisomer, Cis-Trans Curcumin, as a Novel Ligand to A₁ and A₃ Adenosine Receptors

• Главные авторы: Luke J. Hamilton (Автор), Mahesh Pattabiraman (Автор), Haizhen A. Zhong (Автор), Michaela Walker (Автор), Hilary Vaughn (Автор), Surabhi Chandra (Автор)
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• Опубликовано: MDPI AG, 2023-06-01T00:00:00Z.
• Предметы: article
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Adenosine receptors (ARs) are being explored to generate non-opioid pain therapeutics. Vanilloid compounds, curcumin, capsaicin, and vanillin possess antinociceptive properties through their interactions with the transient receptor potential channel family. However, their binding with adenosine rece...