Curcumin Stereoisomer, Cis-Trans Curcumin, as a Novel Ligand to A₁ and A₃ Adenosine Receptors

• Main Authors: Luke J. Hamilton (Author), Mahesh Pattabiraman (Author), Haizhen A. Zhong (Author), Michaela Walker (Author), Hilary Vaughn (Author), Surabhi Chandra (Author)
• Format: Book
• Published: MDPI AG, 2023-06-01T00:00:00Z.
• Subjects: article
• Online Access: Connect to this object online.

Adenosine receptors (ARs) are being explored to generate non-opioid pain therapeutics. Vanilloid compounds, curcumin, capsaicin, and vanillin possess antinociceptive properties through their interactions with the transient receptor potential channel family. However, their binding with adenosine rece...