Cover Image

Immunogenicity and safety of lyophilized and liquid dengue tetravalent vaccine candidate formulations in healthy adults: a randomized, phase 2 clinical trial

Takeda has developed a live-attenuated dengue tetravalent vaccine candidate (TAK-003) which has been shown to be immunogenic with acceptable reactogenicity in phase 1 trials. In agreement with World Health Organization prequalification requirements for dengue vaccines, Takeda has manufactured a lyop...

Full description

Saved in:

Bibliographic Details
Main Authors:	Mark Turner (Author), Athanasia Papadimitriou (Author), Peter Winkle (Author), Nathan Segall (Author), Michael Levin (Author), Matthew Doust (Author), Casey Johnson (Author), Gregg Lucksinger (Author), Carlos Fierro (Author), Paul Pickrell (Author), Marsha Raanan (Author), Vianney Tricou (Author), Astrid Borkowski (Author), Derek Wallace (Author)
Format:	Book
Published:	Taylor & Francis Group, 2020-10-01T00:00:00Z.
Subjects:	article
Online Access:	Connect to this object online.
Tags:	Add Tag No Tags, Be the first to tag this record!

Similar Items

Immunogenicity and safety of concomitant and sequential administration of yellow fever YF-17D vaccine and tetravalent dengue vaccine candidate TAK-003: A phase 3 randomized, controlled study.
by: Vianney Tricou, et al.
Published: (2023)

Immunogenicity and safety of a tetravalent dengue vaccine in dengue-naïve adolescents in Mexico City
by: Shibadas Biswal, et al.
Published: (2021)

Integrated immunogenicity analysis of a tetravalent dengue vaccine up to 4 y after vaccination
by: Claire Vigne, et al.
Published: (2017)

The Immunogenicity and Safety of CYD-Tetravalent Dengue Vaccine (CYD-TDV) in Children and Adolescents: A Systematic Review
by: Raksheeth Agarwal, et al.
Published: (2017)

An open-label, Phase 3 trial of TAK-003, a live attenuated dengue tetravalent vaccine, in healthy US adults: immunogenicity and safety when administered during the second half of a 24-month shelf-life
by: Sanjay S. Patel, et al.
Published: (2023)

Immunogenicity and safety of an investigational tetravalent recombinant subunit vaccine for dengue: results of a Phase I randomized clinical trial in flavivirus-naïve adults
by: Susan B. Manoff, et al.
Published: (2019)

Development and evaluation of a tetravalent botulinum vaccine
by: Dan-Yang Shi, et al.
Published: (2022)

In a randomized trial, the live attenuated tetravalent dengue vaccine TV003 is well-tolerated and highly immunogenic in subjects with flavivirus exposure prior to vaccination.
by: Stephen S Whitehead, et al.
Published: (2017)

Immunogenicity of fractional doses of tetravalent a/c/y/w135 meningococcal polysaccharide vaccine: results from a randomized non-inferiority controlled trial in Uganda.
by: Philippe J Guerin, et al.
Published: (2008)

Long-term immunogenicity and safety of tetravalent dengue vaccine (CYD-TDV) in healthy populations in Singapore and Vietnam: 4-year follow-up of randomized, controlled, phase II trials
by: Ngoc Huu Tran, et al.
Published: (2019)

A randomized, open-label clinical trial to evaluate immunogenicity and safety of an indigenously developed DTwP-Hib tetravalent combination vaccine (Easyfour®-TT) with Quadrovax® in Indian infants
by: Lalitendu Mohanty, et al.
Published: (2017)

A recombinant live attenuated tetravalent vaccine for the prevention of dengue
by: Bruno Guy, et al.
Published: (2017)

Efficacy of tetravalent dengue vaccine: A systematic review and meta-analysis
by: Ashish Wasudeo Khobragade, et al.
Published: (2021)

Challenges to the Design of Clinical Trials for Live-Attenuated Tetravalent Dengue Vaccines.
by: Philip K Russell, et al.
Published: (2016)

Development of Lyophilized Gemini Surfactant-Based Gene Delivery Systems: Influence of Lyophilization on the Structure, Activity and Stability of the Lipoplexes
by: Waleed Mohammed-Saeid, et al.
Published: (2012)

Immunogenicity and safety of the first indigenously developed Indian tetravalent influenza vaccine (split virion) in healthy adults ≥ 18 years of age: A randomized, multicenter, phase II / III clinical trial
by: Shrikant Sharma, et al.
Published: (2018)

Pre-marketing immunogenicity and safety of a lyophilized purified human diploid cell rabies vaccine produced from microcarrier cultures: a randomized clinical trial
by: Xingyu Zhou, et al.
Published: (2019)

Immunogenicity and safety of the first indigenously developed Indian tetravalent influenza vaccine (split virion) in healthy children (6 months to 17 years of age): a randomized, multicenter, phase III clinical trial
by: Sumantra Sarkar, et al.
Published: (2021)

A Bispecific, Tetravalent Antibody Targeting Inflammatory and Pruritogenic Pathways in Atopic Dermatitis
by: Julia Tietz, et al.
Published: (2024)

Genetic and phenotypic characterization of manufacturing seeds for a tetravalent dengue vaccine (DENVax).
by: Claire Y-H Huang, et al.
Published: (2013)

Using the tetravalent meningococcal polysaccharide-protein conjugate vaccine in the prevention of meningococcal disease
by: Sanford R Kimmel
Published: (2008)

Lyophilization of pharmaceutical products: From concept to reality
by: Krisanin Chansanroj, et al.
Published: (2016)

Effectiveness of Lyoprotectants in Protein Stabilization During Lyophilization
by: Vinoothini Karunnanithy, et al.
Published: (2024)

RUBY® - a tetravalent (2+2) bispecific antibody format with excellent functionality and IgG-like stability, pharmacology and developability properties
by: Barnabas Nyesiga, et al.
Published: (2024)

The Effects of Lyophilization on the Physico-Chemical Stability of Sirolimus Liposomes
by: Parvin Zakeri-Milani, et al.
Published: (2013)

Lyophilized Symbiotic Mitigates Mucositis Induced by 5-Fluorouracil
by: Bruna Savassi, et al.
Published: (2021)

Lyophilization of Liposomal Formulations: Still Necessary, Still Challenging
by: Silvia Franzé, et al.
Published: (2018)

Nanoencapsulation as a General Solution for Lyophilization of Labile Substrates
by: Girish Vallerinteavide Mavelli, et al.
Published: (2021)

Calorimetric Investigation of the Relaxation Phenomena in Amorphous Lyophilized Solids
by: Sebastian Groёl, et al.
Published: (2021)

Lyophilization of Nanocapsules: Instability Sources, Formulation and Process Parameters
by: Ghania Degobert, et al.
Published: (2021)

Safety, immunogenicity of lyophilized purified vero cell cultured rabies vaccine administered in Zagreb and Essen regimen in post-exposure subjects: A post-marketing, parallel control clinical trial
by: Lei Zhang, et al.
Published: (2021)

The cytotoxic conjugate of highly internalizing tetravalent antibody for targeting FGFR1-overproducing cancer cells
by: Marta Poźniak, et al.
Published: (2021)

Lyophilized Lipid Liquid Crystalline Nanoparticles as an Antimicrobial Delivery System
by: Muhammed Awad, et al.
Published: (2023)

Rational design of heat stable lyophilized rotavirus vaccine formulations
by: Madhu Madan, et al.
Published: (2018)

A quality by design approach for the development of lyophilized liposomes with simvastatin
by: Alina Porfire, et al.
Published: (2017)

Formulation and Evaluation of Optimized Zaltoprofen Lyophilized Tablets by Zydis Technique
by: Suray A. Hazzaa, et al.
Published: (2017)

Rapid Turbidimetric Assay to Determine the Potency of Daptomycin in Lyophilized Powder
by: Eliane Gandolpho Tótoli, et al.
Published: (2015)

Shelf-Life Evaluation and Lyophilization of PBCA-Based Polymeric Microbubbles
by: Tarun Ojha, et al.
Published: (2019)

Modification of the Physicochemical Properties of Active Pharmaceutical Ingredients via Lyophilization
by: Amir Taldaev, et al.
Published: (2023)

A case-control study to determine the effectiveness of a tetravalent dengue vaccine in the state of Paraná, Brazil
by: José Cássio de Moraes, et al.
Published: (2022)