Discontinuation of tenofovir disoproxil fumarate from initial ART regimens because of renal adverse events: An analysis of data from four multi-country clinical trials.

Discontinuation of tenofovir disoproxil fumarate from initial ART regimens because of renal adverse events: An analysis of data from four multi-country clinical trials.

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Tenofovir disoproxil fumarate (TDF), a potent and commonly used antiretroviral drug, is associated with renal tubular dysfunction and renal adverse events. We evaluated the frequency of, time to, and baseline risk factors for discontinuing TDF from initial antiretroviral therapy (ART) regimens becau...

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Main Authors: McNeil Ngongondo (Author), Justin Ritz (Author), Michael D Hughes (Author), Mitch Matoga (Author), Mina C Hosseinipour (Author), AIDS Clinical Trials Group A5208, A5221, A5175 and A5274 Study Teams (Author)
Format: Book
Published: Public Library of Science (PLoS), 2024-01-01T00:00:00Z.
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