Triiodothyronine acts on DAO to regulate pulmonary fibrosis progression by facilitating cell senescence through the p53/p21 signaling pathway

• Main Authors: Xiaoshu Guo (Author), Kai Xu (Author), Lan Wang (Author), Linke Ding (Author), Wenwen Li (Author), Xinsheng Zhang (Author), Weiming Zhao (Author), Ningdan Wang (Author), Gaiping Wang (Author), Wenyu Zhao (Author), Ivan Rosas (Author), Guoying Yu (Author)
• Format: Book
• Published: Frontiers Media S.A., 2024-09-01T00:00:00Z.
• Subjects: article
• Online Access: Connect to this object online.

BackgroundIdiopathic pulmonary fibrosis (IPF) is the result of multiple cycles of epithelial cell injury and fibroblast activation; currently, there is no clear etiology. Increasing evidence suggests that protein metabolism and amino acids play a crucial role in IPF, but the role of D-amino acids is...