GSK5182, 4-Hydroxytamoxifen Analog, a New Potential Therapeutic Drug for Osteoarthritis

• Glavni autori: Yunhui Min (Autor), Dahye Kim (Autor), Godagama Gamaarachchige Dinesh Suminda (Autor), Xiangyu Zhao (Autor), Mangeun Kim (Autor), Yaping Zhao (Autor), Young-Ok Son (Autor)
• Format: Knjiga
• Izdano: MDPI AG, 2020-11-01T00:00:00Z.
• Teme: article
• Online pristup: Connect to this object online.

Estrogen-related receptors (ERRs) are the first identified orphan nuclear receptors. The ERR family consists of ERRα, ERRβ, and ERRγ, regulating diverse isoform-specific functions. We have reported the importance of ERRγ in osteoarthritis (OA) pathogenesis. However, therapeutic approaches with ERRγ...