GSK5182, 4-Hydroxytamoxifen Analog, a New Potential Therapeutic Drug for Osteoarthritis

• Автори: Yunhui Min (Автор), Dahye Kim (Автор), Godagama Gamaarachchige Dinesh Suminda (Автор), Xiangyu Zhao (Автор), Mangeun Kim (Автор), Yaping Zhao (Автор), Young-Ok Son (Автор)
• Формат: Книга
• Опубліковано: MDPI AG, 2020-11-01T00:00:00Z.
• Предмети: article
• Онлайн доступ: Connect to this object online.

Estrogen-related receptors (ERRs) are the first identified orphan nuclear receptors. The ERR family consists of ERRα, ERRβ, and ERRγ, regulating diverse isoform-specific functions. We have reported the importance of ERRγ in osteoarthritis (OA) pathogenesis. However, therapeutic approaches with ERRγ...