Reciprocity between Regulatory T Cells and Th17 Cells: Relevance to Polarized Immunity in Leprosy.

• Main Authors: Soumi Sadhu (Author), Binod Kumar Khaitan (Author), Beenu Joshi (Author), Utpal Sengupta (Author), Arvind Kumar Nautiyal (Author), Dipendra Kumar Mitra (Author)
• Format: Book
• Published: Public Library of Science (PLoS), 2016-01-01T00:00:00Z.
• Subjects: article
• Online Access: Connect to this object online.

T cell defect is a common feature in lepromatous or borderline lepromatous leprosy (LL/BL) patients in contrast to tuberculoid or borderline tuberculoid type (TT/BT) patients. Tuberculoid leprosy is characterized by strong Th1-type cell response with localized lesions whereas lepromatous leprosy is...