New Heterocyclic Combretastatin A-4 Analogs: Synthesis and Biological Activity of Styryl-2(3<i>H</i>)-benzothiazolones

• Главные авторы: Gjorgji Atanasov (Автор), Rusi I. Rusew (Автор), Vladimir M. Gelev (Автор), Christo D. Chanev (Автор), Rosica Nikolova (Автор), Boris L. Shivachev (Автор), Ognyan I. Petrov (Автор), Margarita D. Apostolova (Автор)
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• Опубликовано: MDPI AG, 2021-12-01T00:00:00Z.
• Предметы: article
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Here, we describe the synthesis, characterization, and biological activities of a series of 26 new styryl-2(3H)-benzothiazolone analogs of combretastatin-A4 (CA-4). The cytotoxic activities of these compounds were tested in several cell lines (EA.hy926, A549, BEAS-2B, MDA-MB-231, HT-29, MCF-7, and M...