Hyperactivity and attention deficits in mice with decreased levels of stress-inducible phosphoprotein 1 (STIP1)

• Main Authors: Flavio H. Beraldo (Author), Anu Thomas (Author), Benjamin Kolisnyk (Author), Pedro H. Hirata (Author), Xavier De Jaeger (Author), Amanda C. Martyn (Author), Jue Fan (Author), Daniela F. Goncalves (Author), Matthew F. Cowan (Author), Talal Masood (Author), Vilma R. Martins (Author), Robert Gros (Author), Vania F. Prado (Author), Marco A. M. Prado (Author)
• Format: Book
• Published: The Company of Biologists, 2015-11-01T00:00:00Z.
• Subjects: article
• Online Access: Connect to this object online.

Stress-inducible phosphoprotein I (STIP1, STI1 or HOP) is a co-chaperone intermediating Hsp70/Hsp90 exchange of client proteins, but it can also be secreted to trigger prion protein-mediated neuronal signaling. Some mothers of children with autism spectrum disorders (ASD) present antibodies against...