Tumor membrane-based vaccine immunotherapy in combination with anti-CTLA-4 antibody confers protection against immune checkpoint resistant murine triple-negative breast cancer

• Главные авторы: Christopher D. Pack (Автор), Ramireddy Bommireddy (Автор), Luis E. Munoz (Автор), Jaina M. Patel (Автор), Erica N. Bozeman (Автор), Paulami Dey (Автор), Vijayaraghavan Radhakrishnan (Автор), Vincent F. Vartabedian (Автор), Kalpana Venkat (Автор), Sampath Ramachandiran (Автор), Shaker J. C. Reddy (Автор), Periasamy Selvaraj (Автор)
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• Опубликовано: Taylor & Francis Group, 2020-12-01T00:00:00Z.
• Предметы: article
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Triple-negative breast cancer (TNBC) afflicts women at a younger age than other breast cancers and is associated with a worse clinical outcome. This poor clinical outcome is attributed to a lack of defined targets and patient-to-patient heterogeneity in target antigens and immune responses. To addre...