Tumor membrane-based vaccine immunotherapy in combination with anti-CTLA-4 antibody confers protection against immune checkpoint resistant murine triple-negative breast cancer

• Main Authors: Christopher D. Pack (Author), Ramireddy Bommireddy (Author), Luis E. Munoz (Author), Jaina M. Patel (Author), Erica N. Bozeman (Author), Paulami Dey (Author), Vijayaraghavan Radhakrishnan (Author), Vincent F. Vartabedian (Author), Kalpana Venkat (Author), Sampath Ramachandiran (Author), Shaker J. C. Reddy (Author), Periasamy Selvaraj (Author)
• Format: Book
• Published: Taylor & Francis Group, 2020-12-01T00:00:00Z.
• Subjects: article
• Online Access: Connect to this object online.

Triple-negative breast cancer (TNBC) afflicts women at a younger age than other breast cancers and is associated with a worse clinical outcome. This poor clinical outcome is attributed to a lack of defined targets and patient-to-patient heterogeneity in target antigens and immune responses. To addre...