Isolation of Trypanosoma brucei gambiense from cured and relapsed sleeping sickness patients and adaptation to laboratory mice.

• Main Authors: Patient Pati Pyana (Author), Ipos Ngay Lukusa (Author), Dieudonné Mumba Ngoyi (Author), Nick Van Reet (Author), Marcel Kaiser (Author), Stomy Karhemere Bin Shamamba (Author), Philippe Büscher (Author)
• Format: Book
• Published: Public Library of Science (PLoS), 2011-01-01T00:00:00Z.
• Subjects: article
• Online Access: Connect to this object online.

BACKGROUND: Sleeping sickness due to Trypanosoma brucei (T.b.) gambiense is still a major public health problem in some central African countries. Historically, relapse rates around 5% have been observed for treatment with melarsoprol, widely used to treat second stage patients. Later, relapse rates...