4-Chlorophenylguanidine is an ASIC3 agonist and positive allosteric modulator

Acid-sensing ion channels (ASICs) are proton-sensitive sodium channels that open in response to lowered extracellular pH and are expressed in the central and peripheral nervous systems. The ASIC3 subtype is found primarily in the periphery where the channel mediates pain signals caused by ischemia a...

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Main Authors: Amruta S. Agharkar (Author), Eric B. Gonzales (Author)
Format: Book
Published: Elsevier, 2017-03-01T00:00:00Z.
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3rd Floor Main Library

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Call Number: A1234.567
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