A Novel Protocol Using Small-Scale Spray-Drying for the Efficient Screening of Solid Dispersions in Early Drug Development and Formulation, as a Straight Pathway from Screening to Manufacturing Stages

This work describes a novel screening strategy that implements small-scale spray-drying in early development of binary amorphous solid dispersions (ASDs). The proposed methodology consists of a three-stage decision protocol in which small batches (20–100 mg) of spray-dried solid dispersion...

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Bibliographic Details
Main Authors: Aymeric Ousset (Author), Rosanna Chirico (Author), Florent Robin (Author), Martin Alexander Schubert (Author), Pascal Somville (Author), Kalliopi Dodou (Author)
Format: Book
Published: MDPI AG, 2018-08-01T00:00:00Z.
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