A Novel Heptapeptide, GPPGPAG Transfers to the Brain, and Ameliorates Memory Dysfunction and Dendritic Atrophy in Alzheimer's Disease Model Mice

• Autores principales: Chihiro Tohda (Autor), Chisato Kogure (Autor), Kaori Nomoto (Autor), Andreia de Toledo (Autor), Ximeng Yang (Autor), Eiichi Hirano (Autor)
• Formato: Libro
• Publicado: Frontiers Media S.A., 2021-05-01T00:00:00Z.
• Materias: article
• Acceso en línea: Connect to this object online.

We investigated the effects of a heptapeptide, GPPGPAG, on memory improvement and neuritic regeneration in Alzheimer's disease models to evaluate its potency as a new anti-Alzheimer's disease (AD) therapy. The anti-AD effects of GPPGPAG were evaluated in Aβ-treated cortical neurons and 5XF...