Protection from Endotoxic Uveitis by Intravitreal Resolvin D1: Involvement of Lymphocytes, miRNAs, Ubiquitin-Proteasome, and M1/M2 Macrophages

• Main Authors: S. Rossi (Author), C. Di Filippo (Author), C. Gesualdo (Author), N. Potenza (Author), A. Russo (Author), M. C. Trotta (Author), M. V. Zippo (Author), R. Maisto (Author), F. Ferraraccio (Author), F. Simonelli (Author), M. D'Amico (Author)
• Format: Book
• Published: Hindawi Limited, 2015-01-01T00:00:00Z.
• Subjects: article
• Online Access: Connect to this object online.

This study investigated the protective effects of intravitreal Resolvin D1 (RvD1) against LPS-induced rat endotoxic uveitis (EIU). RvD1 was administered into the right eye at a single injection of 5 μL volume containing 10-100-1000 ng/kg RvD1 1 h post-LPS injection (200 μg, Salmonella minnesota) int...