CS-semi5 Inhibits NF-κB Activation to Block Synovial Inflammation, Cartilage Loss and Bone Erosion Associated With Collagen-Induced Arthritis

• Principais autores: Xiang Li (Autor), Xiaonan Tang (Autor), Yufei Wang (Autor), Changwei Chai (Autor), Zhehui Zhao (Autor), Haijing Zhang (Autor), Ying Peng (Autor), Lianqiu Wu (Autor)
• Formato: Livro
• Publicado em: Frontiers Media S.A., 2021-07-01T00:00:00Z.
• Assuntos: article
• Acesso em linha: Connect to this object online.

Rheumatoid arthritis (RA) is a chronic, systemic autoimmune disease that affects 1% of the population. CS-semi5 is a semisynthetic chondroitin sulfate. In this study, CS-semi5 was shown to have positive effects on a model of collagen-induced arthritis (CIA). CS-semi5 treatment had obvious effects on...