Musculoskeletal events associated with the management of endocrine-responsive breast cancer

• Main Authors: Anas Al-Janadi (Author), Borys Hrinczenko (Author), Vijay Chaudhary (Author), Shalini Chitneni (Author), Sarah Ali (Author), Jennifer Saultz (Author), Nikolay V. Dimitrov (Author)
• Format: Book
• Published: Frontiers Media S.A., 2011-12-01T00:00:00Z.
• Subjects: article
• Online Access: Connect to this object online.

Musculoskeletal symptoms have been reported in patients treated with third generation aromatase inhibitors (AIs) and with blockers of hypothalamic-pituitary gonadal axis. AIs act by suppressing postmenopausal estrogen biosynthesis through inhibition of the enzyme aromatase, which is responsible for...