TRPC6 gene promoter polymorphisms in steroid resistant nephrotic syndrome children

• Main Authors: Mahesh Kumar Kempanahalli Basappa (Author), Prabha Senguttuvan (Author), Ramprasad Elumalai (Author), Bhaskar Lakkakula VKS (Author), Soundararajan Periasamy (Author)
• Format: Book
• Published: Society of Diabetic Nephropathy Prevention, 2015-04-01T00:00:00Z.
• Subjects: article
• Online Access: Connect to this object online.

Introduction: Nephrotic syndrome (NS) is the most frequent cause of proteinuria in children and is emerging as a leading cause of uremia. Among idiopathic NS, 10% of children do not respond to steroids or to any other immunosuppressive therapy, and progress to end-stage renal disease (ESRD). Several...