Salt Solubility Products of Diprenorphine Hydrochloride, Codeine and Lidocaine Hydrochlorides and Phosphates - Novel Method of Data Analysis Not Dependent on Explicit Solubility Equations

• Autores principales: Gergely Völgyi (Autor), Attila Marosi (Autor), Krisztina Takács-Novák (Autor), Alex Avdeef (Autor)
• Formato: Libro
• Publicado: International Association of Physical Chemists (IAPC), 2013-12-01T00:00:00Z.
• Materias: article
• Acceso en línea: Connect to this object online.

A novel general approach was described to address many of the challenges of salt solubility determination of drug substances, with data processing and refinement of equilibrium constants encoded in the computer program pDISOL-XTM. The new approach was illustrated by the determinations of the solubil...