Proteomics-Based Characterization of miR-574-5p Decoy to CUGBP1 Suggests Specificity for mPGES-1 Regulation in Human Lung Cancer Cells

• Hlavní autoři: Anne C. Emmerich (Autor), Julia Wellstein (Autor), Elena Ossipova (Autor), Isabell Baumann (Autor), Johan Lengqvist (Autor), Kim Kultima (Autor), Per-Johan Jakobsson (Autor), Dieter Steinhilber (Autor), Meike J. Saul (Autor)
• Médium: Kniha
• Vydáno: Frontiers Media S.A., 2020-03-01T00:00:00Z.
• Témata: article
• On-line přístup: Connect to this object online.

MicroRNAs (miRs) are one of the most important post-transcriptional repressors of gene expression. However, miR-574-5p has recently been shown to positively regulate the expression of microsomal prostaglandin E-synthase-1 (mPGES-1), a key enzyme in the prostaglandin E2 (PGE2) biosynthesis, by acting...