Induction of RIPK3/MLKL-mediated necroptosis by Erigeron breviscapus injection exhibits potent antitumor effect

• Main Authors: Xiuping Guo (Author), Rui Li (Author), Jinjin Cui (Author), Chujuan Hu (Author), Haoyang Yu (Author), Ling Ren (Author), Yangyang Cheng (Author), Jiandong Jiang (Author), Xiao Ding (Author), Lulu Wang (Author)
• Format: Book
• Published: Frontiers Media S.A., 2023-06-01T00:00:00Z.
• Subjects: article
• Online Access: Connect to this object online.

Colorectal cancer (CRC) is the second leading cause of tumor-related deaths worldwide. Resistance of tumor cells to drug-induced apoptosis highlights the need for safe and effective antitumor alternatives. Erigeron breviscapus (Dengzhanxixin in China) injection (EBI), extracted from the natural herb...