Reactivation of Denervated Schwann Cells by Embryonic Spinal Cord Neurons to Promote Axon Regeneration and Remyelination

• Main Authors: Xinyu Fang (Author), Chaofan Zhang (Author), Chongjing Zhang (Author), Yuanqing Cai (Author), Zibo Yu (Author), Zida Huang (Author), Wenbo Li (Author), Wenming Zhang (Author)
• Format: Book
• Published: Hindawi Limited, 2019-01-01T00:00:00Z.
• Subjects: article
• Online Access: Connect to this object online.

In peripheral nerve injuries (PNIs) in which proximal axons do not regenerate quickly enough, significant chronic degeneration of Schwann cells (SCs) can occur at the distal stump of the injured nerve and obstruct regeneration. Cell transplantation can delay the degeneration of SCs, but transplanted...