Development of an apolipoprotein E mimetic peptide-lipid conjugate for efficient brain delivery of liposomes

• Main Authors: Naoya Kato (Author), Sakura Yamada (Author), Rino Suzuki (Author), Yoshiki Iida (Author), Makoto Matsumoto (Author), Shintaro Fumoto (Author), Hidetoshi Arima (Author), Hidefumi Mukai (Author), Shigeru Kawakami (Author)
• Format: Book
• Published: Taylor & Francis Group, 2023-12-01T00:00:00Z.
• Subjects: article
• Online Access: Connect to this object online.

AbstractLiposomes are versatile carriers that can encapsulate various drugs; however, for delivery to the brain, they must be modified with a targeting ligand or other modifications to provide blood-brain barrier (BBB) permeability, while avoiding rapid clearance by reticuloendothelial systems throu...