Fabrication and Appraisal of Simvastatin via Tailored Niosomal Nanovesicles for Transdermal Delivery Enhancement: In Vitro and In Vivo Assessment

Simvastatin (SIM) is a HMG-CoA reductase inhibitor employed in the management of hyperlipidemia. However, its low bioavailability limits its clinical efficacy. The objective of this study was to overcome the poor bioavailability of SIM via the transdermal application of a SIM-loaded niosomal gel. Ni...

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Main Authors: Heba F. Salem (Author), Rasha M. Kharshoum (Author), Heba A. Abou-Taleb (Author), Hanan Osman Farouk (Author), Randa Mohammed Zaki (Author)
Format: Book
Published: MDPI AG, 2021-01-01T00:00:00Z.
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3rd Floor Main Library

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