Hypoxia-induced NLRP3 inflammasome activation via the HIF-1α/NF-κB signaling pathway in human dental pulp fibroblasts

• Автори: Diya Wang (Автор), Minghao Wang (Автор), Shukai Sun (Автор), Chongyang Zhang (Автор), Ya Song (Автор), Jianing Li (Автор), Bing Song (Автор), Haipeng Lv (Автор), Shengchao Wang (Автор), Wenkai Jiang (Автор)
• Формат: Книга
• Опубліковано: BMC, 2024-09-01T00:00:00Z.
• Предмети: article
• Онлайн доступ: Connect to this object online.

Abstract Background Previous studies have reported the link between hypoxic conditions and NLRP3 inflammasome-mediated pulpal inflammation in the progression of pulpitis. However, the underlying mechanism has not been fully elucidated. This study aimed to investigate the role of HIF-1α in the regula...