Suppression of FGF5 and FGF18 Expression by Cholesterol-Modified siRNAs Promotes Hair Growth in Mice

• Main Authors: Jungang Zhao (Author), Haojie Lin (Author), Lusheng Wang (Author), Keke Guo (Author), Rongrong Jing (Author), Xuenan Li (Author), Yu Chen (Author), Zhenlin Hu (Author), Shuang Gao (Author), Nuo Xu (Author)
• Format: Book
• Published: Frontiers Media S.A., 2021-07-01T00:00:00Z.
• Subjects: article
• Online Access: Connect to this object online.

FGF5 and FGF18 are key factors in the regulation of the hair follicle cycle. FGF5 is overexpressed during the late anagen phase and serves as a crucial regulatory factor that promotes the anagen-to-catagen transition in the hair follicle cycle. FGF18, which is overexpressed during the telogen phase,...