Design, synthesis, in vitro anticancer evaluation, kinase inhibitory effects, and pharmacokinetic profile of new 1,3,4-triarylpyrazole derivatives possessing terminal sulfonamide moiety

The present work describes the design and synthesis of a novel series of 1,3-diaryl-4-sulfonamidoarylpyrazole derivatives 1a-q and 2a-q and their in vitro biological activities. The target compounds were evaluated for antiproliferative activity against NCI-60 cell line panel. Compounds 1c, 1g, 1k-m,...

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Main Authors: Mohammed S. Abdel-Maksoud (Author), Mohammed I. El-Gamal (Author), Mahmoud M. Gamal El-Din (Author), Chang Hyun Oh (Author)
Format: Book
Published: Taylor & Francis Group, 2019-01-01T00:00:00Z.
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3rd Floor Main Library

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Call Number: A1234.567
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