Symmetric molecules with 1,4-triazole moieties as potent inhibitors of tumour-associated lactate dehydrogenase-A

Symmetric molecules with 1,4-triazole moieties as potent inhibitors of tumour-associated lactate dehydrogenase-A

A series of symmetric molecules incorporating aryl or pyridyl moieties as central core and 1,4-substituted triazoles as a side bridge was synthesised. The new compounds were investigated as lactate dehydro-genase (LDH, EC 1.1.1.27) inhibitors. The cancer associated LDHA isoform was inhibited with IC...

Full description

Saved in:
Bibliographic Details
Main Authors: Abdul-Malek S. Altamimi (Author), Ahmed M. Alafeefy (Author), Agnese Balode (Author), Igor Vozny (Author), Aleksandrs Pustenko (Author), Mohey Eldin El Shikh (Author), Fatmah A. S. Alasmary (Author), Sherif A. Abdel-Gawad (Author), Raivis Žalubovskis (Author)
Format: Book
Published: Taylor & Francis Group, 2018-01-01T00:00:00Z.
Subjects:
article
Online Access:Connect to this object online.
Tags: Add Tag
No Tags, Be the first to tag this record!

Internet

Connect to this object online.

3rd Floor Main Library

Holdings details from 3rd Floor Main Library
Call Number: A1234.567
Copy 1 Available

Similar Items