Case Report: Arterial Wall Inflammation in Atherosclerotic Cardiovascular Disease is Reduced by Olamkicept (sgp130Fc)

• Main Authors: Dominik M. Schulte (Author), Georg H. Waetzig (Author), Harald Schuett (Author), Marlies Marx (Author), Berenice Schulte (Author), Christoph Garbers (Author), Juliane Lokau (Author), Ann-Kathrin Vlacil (Author), Juliane Schulz (Author), Anna K. Seoudy (Author), Bernhard Schieffer (Author), Philip Rosenstiel (Author), Marcus Seeger (Author), Matthias Laudes (Author), Stefan Rose-John (Author), Ulf Lützen (Author), Karsten Grote (Author), Stefan Schreiber (Author)
• Format: Book
• Published: Frontiers Media S.A., 2022-06-01T00:00:00Z.
• Subjects: article
• Online Access: Connect to this object online.

Inflammation is a strong driver of atherosclerotic cardiovascular disease (ASCVD). There is a large unmet need for therapies that prevent or reduce excessive inflammation while avoiding systemic immunosuppression. We showed previously that selective inhibition of pro-inflammatory interleukin-6 (IL-6...