Liujunzi decoction attenuates cisplatin-induced anorexia in rats via inhibiting PERK/eIF2α/ATF4/CHOP pathway and GDF15/GFRAL expression

• Main Authors: Yongzhao Dai (Author), Wanting Hu (Author), Jinyuan Han (Author), Yaozhong Zhao (Author), Xipei Wu (Author), Xiuxiu Liao (Author), Ke Nie (Author)
• Format: Book
• Published: KeAi Communications Co., Ltd., 2024-06-01T00:00:00Z.
• Subjects: article
• Online Access: Connect to this object online.

Background and aim: Liujunzi Decoction (LJZD), also called Rikkunshito, is a traditional formula that has proven effective in clinical treatment against chemotherapy-induced anorexia (CIA). Previous study indicated the importance of GDF15/GFRAL axis in the pathogenesis of CIA, and suggested the pote...