aThe characteristics of glucose metabolism in the sulfonylurea receptor 1 knockout rat model

• Main Authors: Xiaojun Zhou (Author), Chunmei Xu (Author), Zhiwei Zou (Author), Xue Shen (Author), Tianyue Xie (Author), Rui Zhang (Author), Lin Liao (Author), Jianjun Dong (Author)
• Format: Book
• Published: BMC, 2019-01-01T00:00:00Z.
• Subjects: article
• Online Access: Connect to this object online.

Abstract Background Sulfonylurea receptor 1 (SUR1) is primarily responsible for glucose regulation in normal conditions. Here, we sought to investigate the glucose metabolism characteristics of SUR1 −/− rats. Methods The TALEN technique was used to construct a SUR1 gene deficiency rat model. Rats we...