Improving the Antitumor Activity and Bioavailability of Sonidegib for the Treatment of Skin Cancer

• Hoofdauteurs: Amr Gamal (Auteur), Haitham Saeed (Auteur), Fatma I. Abo El-Ela (Auteur), Heba F. Salem (Auteur)
• Formaat: Boek
• Gepubliceerd in: MDPI AG, 2021-09-01T00:00:00Z.
• Onderwerpen: article
• Online toegang: Connect to this object online.

Throughout the United States and the world, skin cancer is the most frequent form of cancer. Sonidegib (SNG) is a hedgehog inhibitor that has been used for skin cancer treatment. However, SNG has low bioavailability and is associated with resistance. The focus of this work is to enhance bioavailabil...