Resolvin E3 attenuates lipopolysaccharide-induced depression-like behavior in mice

• Main Authors: Satoshi Deyama (Author), Kento Shimoda (Author), Hiroyuki Ikeda (Author), Hayato Fukuda (Author), Satoshi Shuto (Author), Masabumi Minami (Author)
• Format: Book
• Published: Elsevier, 2018-09-01T00:00:00Z.
• Subjects: article
• Online Access: Connect to this object online.

Eicosapentaenoic acid (EPA)-derived resolvin E1 (RvE1) and E2 (RvE2) have antidepressant effects. Here, we investigated the antidepressant effects of resolvin E3 (RvE3) in a mouse model of lipopolysaccharide (LPS)-induced depression. We observed that LPS (0.8 mg/kg, i.p.) significantly increased imm...