PCR amplicons identify widespread copy number variation in human centromeric arrays and instability in cancer

Summary: Centromeric α-satellite repeats represent ∼6% of the human genome, but their length and repetitive nature make sequencing and analysis of those regions challenging. However, centromeres are essential for the stable propagation of chromosomes, so tools are urgently needed to monitor centrome...

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Príomhchruthaitheoirí: Leonardo Gomes de Lima (Údar), Edmund Howe (Údar), Vijay Pratap Singh (Údar), Tamara Potapova (Údar), Hua Li (Údar), Baoshan Xu (Údar), Jemma Castle (Údar), Steve Crozier (Údar), Christine J. Harrison (Údar), Steve C. Clifford (Údar), Karen H. Miga (Údar), Sarra L. Ryan (Údar), Jennifer L. Gerton (Údar)
Formáid: LEABHAR
Foilsithe / Cruthaithe: Elsevier, 2021-12-01T00:00:00Z.
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