Implementation of a Design of Experiments to Improve Periplasmic Yield of Functional ScFv Antibodies in a Phage Display Platform

Implementation of a Design of Experiments to Improve Periplasmic Yield of Functional ScFv Antibodies in a Phage Display Platform

Purpose: Production of functional recombinant antibody fragments in the periplasm of E. coli isa prerequisite step to achieve sufficient reagent for preclinical studies. Thus, the cost-effectiveand lab-scale production of antibody fragments demands the optimization of culture conditions.Methods: The...

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Main Authors: Marjan Abri Aghdam (Author), Mohammad Reza Tohidkia (Author), Elham Ghamghami (Author), Asadollah Ahmadikhah (Author), Morteza Khanmahamadi (Author), Behzad Baradaran (Author), Ahad Mokhtarzadeh (Author)
Format: Book
Published: Tabriz University of Medical Sciences, 2022-05-01T00:00:00Z.
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3rd Floor Main Library

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