Screening and computational analysis of colorectal associated non-synonymous polymorphism in CTNNB1 gene in Pakistani population

• मुख्य लेखकों: Suhail Razak (लेखक), Nousheen Bibi (लेखक), Javid Ahmad Dar (लेखक), Tayyaba Afsar (लेखक), Ali Almajwal (लेखक), Zahida Parveen (लेखक), Sarwat Jahan (लेखक)
• स्वरूप: पुस्तक
• प्रकाशित: BMC, 2019-11-01T00:00:00Z.
• विषय: article
• ऑनलाइन पहुंच: Connect to this object online.

Abstract Background Colorectal cancer (CRC) is categorized by alteration of vital pathways such as β-catenin (CTNNB1) mutations, WNT signaling activation, tumor protein 53 (TP53) inactivation, BRAF, Adenomatous polyposis coli (APC) inactivation, KRAS, dysregulation of epithelial to mesenchymal trans...