Overexpression of Beclin1 enhances autophagy and inhibits epithelial mesenchymal transition in melanoma A375 cells

• Main Authors: Zhao HAN (Author), Yanling GAO (Author), Jianzhong ZHANG (Author), Ling ZHANG (Author), Yanyan XU (Author), Xiaojing LI (Author)
• Format: Book
• Published: editoiral office of Journal of Diagnosis and Therapy on Dermato-venereology, 2022-06-01T00:00:00Z.
• Subjects: article
• Online Access: Connect to this object online.

Objective To investigate the effect of Beclin1 overexpression on autophagy and EMT in melanoma A375 cells. Methods Human malignant melanoma A375 cells were divided into three groups by liposome transfection, i.e., blank group(no plasmid), NC group(transfection empty plasmid), and transfection group(...