Effects of prophylactic ibuprofen and paracetamol administration on the immunogenicity and reactogenicity of the 10-valent pneumococcal non-typeable Haemophilus influenzae protein D conjugated vaccine (PHiD-CV) co-administered with DTPa-combined vaccines in children: An open-label, randomized, controlled, non-inferiority trial

• Main Authors: Oana Falup-Pecurariu (Author), Sorin C. Man (Author), Mihai L. Neamtu (Author), Gratiana Chicin (Author), Ginel Baciu (Author), Carmen Pitic (Author), Alexandra C. Cara (Author), Andrea E. Neculau (Author), Marin Burlea (Author), Ileana L. Brinza (Author), Cristina N. Schnell (Author), Valentina Sas (Author), Valeriu V. Lupu (Author), Nancy François (Author), Kristien Swinnen (Author), Dorota Borys (Author)
• Format: Book
• Published: Taylor & Francis Group, 2017-03-01T00:00:00Z.
• Subjects: article
• Online Access: Connect to this object online.

Prophylactic paracetamol administration impacts vaccine immune response; this study (www.clinicaltrials.gov: NCT01235949) is the first to assess PHiD-CV immunogenicity following prophylactic ibuprofen administration. In this phase IV, multicenter, open-label, randomized, controlled, non-inferiority...