Antileishmanial activity of sulphonamide nanoemulsions targeting the β-carbonic anhydrase from Leishmania species

The β-carbonic anhydrase (CA, EC 4.2.1.1) from Leishmania spp. (LdcCA) is effectively inhibited by aromatic/heterocyclic sulphonamides, in the low nanomolar range, but no in vitro antileishmanial activity was detected for such compounds. We formulated some of these sulphonamides as nanoemulsions (NE...

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Main Authors: Verônica da Silva Cardoso (Author), Alane Beatriz Vermelho (Author), Eduardo Ricci Junior (Author), Igor Almeida Rodrigues (Author), Ana Maria Mazotto (Author), Claudiu T. Supuran (Author)
Format: Book
Published: Taylor & Francis Group, 2018-01-01T00:00:00Z.
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3rd Floor Main Library

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Call Number: A1234.567
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