Sodium Dichloroacetate Stimulates Angiogenesis by Improving Endothelial Precursor Cell Function in an AKT/GSK-3β/Nrf2 Dependent Pathway in Vascular Dementia Rats

• 主要な著者: Hui Zhao (著者), Junqin Mao (著者), Yuan Yuan (著者), Jingjing Feng (著者), Hao Cheng (著者), Guorong Fan (著者), Yuefan Zhang (著者), Tiejun Li (著者)
• フォーマット: 図書
• 出版事項: Frontiers Media S.A., 2019-05-01T00:00:00Z.
• 主題: article
• オンライン･アクセス: Connect to this object online.

Sodium dichloroacetate (DCA) is a mitochondrial pyruvate dehydrogenase kinase inhibitor, and has been shown to display vasoprotective effects in chronic ischemic stroke. The purpose of this study was to evaluate the therapeutic effect of DCA on vascular dementia (VD) and endothelial progenitor cell...