Carbonic Anhydrase IX-Targeted α-Radionuclide Therapy with 225Ac Inhibits Tumor Growth in a Renal Cell Carcinoma Model

Carbonic Anhydrase IX-Targeted α-Radionuclide Therapy with 225Ac Inhibits Tumor Growth in a Renal Cell Carcinoma Model

In this study, we compared the tumor-targeting properties, therapeutic efficacy, and tolerability of the humanized anti-CAIX antibody (hG250) labeled with either the α-emitter actinium-225 (<sup>225</sup>Ac) or the β<sup>-</sup>-emitter lutetium-177 (<sup>177</sup>...

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Main Authors: Robin I. J. Merkx (Author), Mark Rijpkema (Author), Gerben M. Franssen (Author), Annemarie Kip (Author), Bart Smeets (Author), Alfred Morgenstern (Author), Frank Bruchertseifer (Author), Eddie Yan (Author), Michael P. Wheatcroft (Author), Egbert Oosterwijk (Author), Peter F. A. Mulders (Author), Sandra Heskamp (Author)
Format: Book
Published: MDPI AG, 2022-05-01T00:00:00Z.
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3rd Floor Main Library

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