Investigation of simplified physiologically‐based pharmacokinetic models in rat and human

• প্রধান লেখক: Estelle Yau (লেখক), Andrés Olivares‐Morales (লেখক), Kayode Ogungbenro (লেখক), Leon Aarons (লেখক), Michael Gertz (লেখক)
• বিন্যাস: গ্রন্থ
• প্রকাশিত: Wiley, 2023-03-01T00:00:00Z.
• বিষয়গুলি: article
• অনলাইন ব্যবহার করুন: Connect to this object online.

Abstract Whole‐body physiologically‐based pharmacokinetic (PBPK) models have many applications in drug research and development. It is often necessary to inform these models with animal or clinical data, updating model parameters, and making the model more predictive for future applications. This pr...