Investigation of simplified physiologically‐based pharmacokinetic models in rat and human

• Những tác giả chính: Estelle Yau (Tác giả), Andrés Olivares‐Morales (Tác giả), Kayode Ogungbenro (Tác giả), Leon Aarons (Tác giả), Michael Gertz (Tác giả)
• Định dạng: Sách
• Được phát hành: Wiley, 2023-03-01T00:00:00Z.
• Những chủ đề: article
• Truy cập trực tuyến: Connect to this object online.

Abstract Whole‐body physiologically‐based pharmacokinetic (PBPK) models have many applications in drug research and development. It is often necessary to inform these models with animal or clinical data, updating model parameters, and making the model more predictive for future applications. This pr...