Impact of dosing strategies on plasma concentrations of tenofovir: Implications in HIV pre-exposure prophylaxis in China

• Autors principals: Jingchuan Shang (Autor), Rui Tan (Autor), Junqing Yang (Autor), Bo Yan (Autor), Xiaoni Zhong (Autor), Yan Zhang (Autor), Bayan Alnajebi (Autor), Qing Ma (Autor), Ailong Huang (Autor)
• Format: Llibre
• Publicat: Elsevier, 2021-09-01T00:00:00Z.
• Matèries: article
• Accés en línia: Connect to this object online.

Background: Tenofovir disoproxil fumarate has been recommended for pre-exposure prophylaxis (PrEP) to prevent HIV infection. Several studies have shown short but potent intermittent PrEP could provide comparable protection to daily PrEP in men, suggesting such dosing strategy might be useful in Chin...